Comparison of Risk Factors Prevalence, Type of Therapy and Mortality Due to Myocardial Infarction in Diabetic and Non-Diabetic Elderly: Results from Cohort Study

Objectives: Elder Myocardial infarction diabetic patients are vulnerable, considering the importance of this issue, our aim in this study was to compare the prevalence of risk factors, type of reperfusion therapy and mortality of elderly MI patients in diabetic and non-diabetic groups. Methods: The present study is a cohort and its participants included 1460 elderly patients who were admitted to Kermanshah Imam Ali (AS) Hospital from 2016 to 2019 as part of the STEMI patient registry program. After completing the informed consent form and based on the inclusion criteria, divided into diabetic and non-diabetic groups. Patients' information was completed in the checklist including demographic status, medical history, cardiovascular risk factors, clinical and diagnostic tests, treatment and mortality at the time of admission, hospitalization and at the time of discharge by trained nurses. Data analysis was performed using descriptive statistics, independent t-test, Mann-Whitney and Chi-square test in Stata software version 14, and P <0.05 was considered as significant level. Results: The results of the present study showed that the number of diabetic women (47.11%) was significantly (p <0.001) higher than the number of women in the non-diabetic group (25.60%). also, the prevalence of mean LDL and cholesterol levels in non-diabetics was significantly (p <0.001) higher than diabetics. The mean prevalence of HDL was not significantly different between the two groups (p <0.777). Prevalence of BMI≥30, history of myocardial infarction, hyperlipidemia, hypertension, triglyceride and GFR <60 was significantly higher in diabetics than non-diabetics while in the non-diabetic elderly, LDL and high cholesterol were more prevalent. Our study results, by providing a scientific model based on registry data, provide useful information to experts in this field to develop lifestyle improvement programs, make drug prescribing more targeted, and raise awareness specifically for this group of patients. Conclusion: Prevalence of some myocardial infarction risk factors in diabetic and non-diabetic elderly is different and the results of this study provide a scientific model based on registry data to provide useful information to experts in this field to develop lifestyle modification programs with more targeted drug prescribing and provides awareness specifically in this group of patients.